Alterations to mTORC1 signaling in the skeletal muscle differentially affect whole-body metabolism

BACKGROUND: The mammalian target of rapamycin complex 1 (mTORC1) is a central node in a network of signaling pathways controlling cell growth and survival. This multiprotein complex integrates external signals and affects different nutrient pathways in various organs. However, it is not clear how al...

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Bibliographic Details
Published in:Skelet Muscle
Main Authors: Guridi, Maitea, Kupr, Barbara, Romanino, Klaas, Lin, Shuo, Falcetta, Denis, Tintignac, Lionel, Rüegg, Markus A.
Format: Artigo
Language:Inglês
Published: BioMed Central 2016
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4800774/
https://ncbi.nlm.nih.gov/pubmed/27004103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13395-016-0084-8
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