Differential response of skeletal muscles to mTORC1 signaling during atrophy and hypertrophy

BACKGROUND: Skeletal muscle mass is determined by the balance between protein synthesis and degradation. Mammalian target of rapamycin complex 1 (mTORC1) is a master regulator of protein translation and has been implicated in the control of muscle mass. Inactivation of mTORC1 by skeletal muscle-spec...

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Detalhes bibliográficos
Main Authors: Bentzinger, C Florian, Lin, Shuo, Romanino, Klaas, Castets, Perrine, Guridi, Maitea, Summermatter, Serge, Handschin, Christoph, Tintignac, Lionel A, Hall, Michael N, Rüegg, Markus A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3622636/
https://ncbi.nlm.nih.gov/pubmed/23497627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2044-5040-3-6
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