mTORC2 affects the maintenance of the muscle stem cell pool

BACKGROUND: The mammalian target of rapamycin complex 2 (mTORC2), containing the essential protein rictor, regulates cellular metabolism and cytoskeletal organization by phosphorylating protein kinases, such as PKB/Akt, PKC, and SGK. Inactivation of mTORC2 signaling in adult skeletal muscle affects...

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Dettagli Bibliografici
Pubblicato in:Skelet Muscle
Autori principali: Rion, Nathalie, Castets, Perrine, Lin, Shuo, Enderle, Leonie, Reinhard, Judith R., Rüegg, Markus A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2019
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6886171/
https://ncbi.nlm.nih.gov/pubmed/31791403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13395-019-0217-y
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