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Editing DNA Methylation in Mammalian Embryos
DNA methylation in mammals is essential for numerous biological functions, such as ensuring chromosomal stability, genomic imprinting, and X-chromosome inactivation through transcriptional regulation. Gene knockout of DNA methyltransferases and demethylation enzymes has made significant contribution...
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| Publicado no: | Int J Mol Sci |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7014263/ https://ncbi.nlm.nih.gov/pubmed/31963664 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21020637 |
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