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Editing DNA methylation in the mammalian genome
Mammalian DNA methylation is a critical epigenetic mechanism orchestrating gene expression networks in many biological processes. However, investigation of the functions of specific methylation events remains challenging. Here, we demonstrate that fusion of Tet1 or Dnmt3a with a catalytically inacti...
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| Publicado no: | Cell |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5062609/ https://ncbi.nlm.nih.gov/pubmed/27662091 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.08.056 |
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