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Tracing dynamic changes of DNA methylation at single cell resolution

Mammalian DNA methylation plays an essential role in development. To date, only snapshots of different mouse and human cell types have been generated, providing a static view on DNA methylation. To enable monitoring of methylation status as it changes over time, we establish a Reporter of Genomic Me...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Stelzer, Yonatan, Shivalila, Chikdu Shakti, Soldner, Frank, Markoulaki, Styliani, Jaenisch, Rudolf
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4583717/
https://ncbi.nlm.nih.gov/pubmed/26406378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.08.046
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