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Targeted DNA methylation in pericentromeres with genome editing-based artificial DNA methyltransferase
To study the impact of epigenetic changes on biological functions, the ability to manipulate the epigenetic status of certain genomic regions artificially could be an indispensable technology. “Epigenome editing” techniques have gradually emerged that apply TALE or CRISPR/Cas9 technologies with vari...
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Publicado no: | PLoS One |
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Main Authors: | , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5436701/ https://ncbi.nlm.nih.gov/pubmed/28542388 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0177764 |
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