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Nucleotide Sugar Pucker Preference Mitigates Excision by HIV-1 RT
A series of DNA primers containing nucleotides with various sugar pucker conformations at the 3′-terminus were chemically synthesized by solid-phase synthesis. The ability of wild-type (WT) HIV-1 reverse transcriptase (RT) and AZT-resistant (AZTr) RT to excise the 3′-terminal nucleotide was assessed...
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| Publicado no: | ACS Chem Biol |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7012501/ https://ncbi.nlm.nih.gov/pubmed/26131619 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.5b00263 |
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