Positional Scanning MUC1 Glycopeptide Library Reveals the Importance of PDTR Epitope Glycosylation for Lectin Binding

[Image: see text] One of the main barriers to explaining the functional significance of glycan-based changes in cancer is the natural epitope heterogeneity found on the surface of cancer cells. To help address this knowledge gap, we focused on designing synthetic tools to explore the role of tumor-a...

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Bibliografiska uppgifter
I publikationen:J Org Chem
Huvudupphovsmän: Singh, YashoNandini, Rodriguez Benavente, Maria C., Al-Huniti, Mohammed H., Beckwith, Donella, Ayyalasomayajula, Ramya, Patino, Eric, Miranda, William S., Wade, Alex, Cudic, Maré
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Chemical Society 2019
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7012140/
https://ncbi.nlm.nih.gov/pubmed/31799848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.9b02396
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