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Positional Scanning MUC1 Glycopeptide Library Reveals the Importance of PDTR Epitope Glycosylation for Lectin Binding

[Image: see text] One of the main barriers to explaining the functional significance of glycan-based changes in cancer is the natural epitope heterogeneity found on the surface of cancer cells. To help address this knowledge gap, we focused on designing synthetic tools to explore the role of tumor-a...

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Detalhes bibliográficos
Publicado no:J Org Chem
Main Authors: Singh, YashoNandini, Rodriguez Benavente, Maria C., Al-Huniti, Mohammed H., Beckwith, Donella, Ayyalasomayajula, Ramya, Patino, Eric, Miranda, William S., Wade, Alex, Cudic, Maré
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2019
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7012140/
https://ncbi.nlm.nih.gov/pubmed/31799848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.9b02396
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