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TF-containing MUC1 glycopeptides fail to entice Galectin-1 recognition of tumor-associated Thomsen-Freidenreich (TF) antigen (CD176) in solution

Aberrant Mucin-1 (MUC1) glycosylation with the Thomsen-Friedenreich (TF) tumor-associated antigen (CD176) is a hallmark of epithelial carcinoma progression and poor patient prognosis. Recognition of TF by glycan-binding proteins, such as galectins, enables the pathological repercussions of this glyc...

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Detalhes bibliográficos
Publicado no:Glycoconj J
Main Authors: FitzGerald, Forrest G., Rodriguez Benavente, Maria C., Garcia, Camelia, Rivero, Yaima, Singh, YashoNandini, Wang, Hongjie, Fields, Gregg B., Cudic, Maré
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7680447/
https://ncbi.nlm.nih.gov/pubmed/33001366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10719-020-09951-x
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