Small‐molecule inhibitors of ubiquitin‐specific protease 7 enhance type‐I interferon antiviral efficacy by destabilizing SOCS1

Type‐I interferons (IFN‐I) are used as common antiviral drugs for a range of viral diseases in clinic. However, the antiviral efficacy of IFN‐I is largely restricted by negative regulators of IFN‐I signaling in cells. Therefore, identification of intracellular inhibitors of IFN‐I signaling is import...

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Detalhes bibliográficos
Publicado no:Immunology
Main Authors: Yuan, Yukang, Miao, Ying, Zeng, Chenhua, Liu, Jin, Chen, Xiangjie, Qian, Liping, Wang, Xiaofang, Qian, Feng, Yu, Zhengyuan, Wang, Jun, Qian, Guanghui, Fu, Qian, Lv, Haitao, Zheng, Hui
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7011631/
https://ncbi.nlm.nih.gov/pubmed/31691271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.13147
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