Small‐molecule inhibitors of ubiquitin‐specific protease 7 enhance type‐I interferon antiviral efficacy by destabilizing SOCS1

Type‐I interferons (IFN‐I) are used as common antiviral drugs for a range of viral diseases in clinic. However, the antiviral efficacy of IFN‐I is largely restricted by negative regulators of IFN‐I signaling in cells. Therefore, identification of intracellular inhibitors of IFN‐I signaling is import...

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Bibliografiska uppgifter
I publikationen:Immunology
Huvudupphovsmän: Yuan, Yukang, Miao, Ying, Zeng, Chenhua, Liu, Jin, Chen, Xiangjie, Qian, Liping, Wang, Xiaofang, Qian, Feng, Yu, Zhengyuan, Wang, Jun, Qian, Guanghui, Fu, Qian, Lv, Haitao, Zheng, Hui
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2019
Ämnen:
Original Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7011631/
https://ncbi.nlm.nih.gov/pubmed/31691271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.13147
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