Small‐molecule inhibitors of ubiquitin‐specific protease 7 enhance type‐I interferon antiviral efficacy by destabilizing SOCS1

Type‐I interferons (IFN‐I) are used as common antiviral drugs for a range of viral diseases in clinic. However, the antiviral efficacy of IFN‐I is largely restricted by negative regulators of IFN‐I signaling in cells. Therefore, identification of intracellular inhibitors of IFN‐I signaling is import...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Immunology
Egile Nagusiak: Yuan, Yukang, Miao, Ying, Zeng, Chenhua, Liu, Jin, Chen, Xiangjie, Qian, Liping, Wang, Xiaofang, Qian, Feng, Yu, Zhengyuan, Wang, Jun, Qian, Guanghui, Fu, Qian, Lv, Haitao, Zheng, Hui
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2019
Gaiak:
Original Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7011631/
https://ncbi.nlm.nih.gov/pubmed/31691271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.13147
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