PGC-1α isoforms coordinate to balance hepatic metabolism and apoptosis in inflammatory environments

OBJECTIVE: The liver is regularly exposed to changing metabolic and inflammatory environments. It must sense and adapt to metabolic need while balancing resources required to protect itself from insult. Peroxisome proliferator activated receptor gamma coactivator-1 alpha (PGC-1α) is a transcriptiona...

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Udgivet i:Mol Metab
Main Authors: Léveillé, Mélissa, Besse-Patin, Aurèle, Jouvet, Nathalie, Gunes, Aysim, Sczelecki, Sarah, Jeromson, Stewart, Khan, Naveen P., Baldwin, Cindy, Dumouchel, Annie, Correia, Jorge C., Jannig, Paulo R., Boulais, Jonathan, Ruas, Jorge L., Estall, Jennifer L.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2020
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7011010/
https://ncbi.nlm.nih.gov/pubmed/32180561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2020.01.004
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