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A PGC-1α isoform induced by resistance training regulates skeletal muscle hypertrophy

PGC-1α is a transcriptional coactivator induced by exercise that gives muscle many of the best known adaptations to endurance-type exercise, but has no effects on muscle strength or hypertrophy. We have identified a novel form of PGC-1α (PGC-1α4) that results from alternative promoter usage and spli...

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Detalhes bibliográficos
Main Authors: Ruas, Jorge L., White, James P., Rao, Rajesh R., Kleiner, Sandra, Brannan, Kevin T., Harrison, Brooke C., Greene, Nicholas P., Wu, Jun, Estall, Jennifer L., Irving, Brian A., Lanza, Ian R., Rasbach, Kyle A., Okutsu, Mitsuharu, Nair, K. Sreekumaran, Yan, Zhen, Leinwand, Leslie A., Spiegelman, Bruce M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3520615/
https://ncbi.nlm.nih.gov/pubmed/23217713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.10.050
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