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Endoplasmic reticulum stress promotes inflammation-mediated proteolytic activity at the ocular surface
A growing body of evidence implicates endoplasmic reticulum (ER) stress in the pathogenesis of chronic inflammatory and autoimmune disorders. Here, we demonstrate that the proinflammatory cytokine TNFα stimulates matrix metalloproteinase 9 (MMP9) at the ocular surface through a c-Fos-dependent mecha...
Enregistré dans:
| Publié dans: | Sci Rep |
|---|---|
| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group UK
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7010695/ https://ncbi.nlm.nih.gov/pubmed/32042069 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-59237-3 |
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