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Endoplasmic reticulum stress promotes inflammation-mediated proteolytic activity at the ocular surface
A growing body of evidence implicates endoplasmic reticulum (ER) stress in the pathogenesis of chronic inflammatory and autoimmune disorders. Here, we demonstrate that the proinflammatory cytokine TNFα stimulates matrix metalloproteinase 9 (MMP9) at the ocular surface through a c-Fos-dependent mecha...
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| 出版年: | Sci Rep |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7010695/ https://ncbi.nlm.nih.gov/pubmed/32042069 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-59237-3 |
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