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Inflammation and endoplasmic reticulum stress in obesity and diabetes
Obesity is associated with chronic low-grade inflammation. Inflammatory signals interfere with insulin action and disrupt metabolic homeostasis. The c-Jun N-terminal kinase (JNK) has been identified as a central mediator of insulin resistance. Recent studies showed that in obesity compromising endop...
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| Главный автор: | |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2885768/ https://ncbi.nlm.nih.gov/pubmed/19136991 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ijo.2008.238 |
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