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S-Nitrosylation links obesity-associated inflammation to endoplasmic reticulum dysfunction

The association between inflammation and endoplasmic reticulum (ER) stress has been observed in many diseases. However, if and how chronic inflammation regulates the unfolded protein response (UPR) and alters ER homeostasis in general, or in the context of chronic disease, remains unknown. Here, we...

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Библиографические подробности
Опубликовано в: :Science
Главные авторы: Yang, Ling, Calay, Ediz S., Fan, Jason, Arduini, Alessandro, Kunz, Ryan C., Gygi, Steven P., Yalcin, Abdullah, Fu, Suneng, Hotamisligil, Gökhan S.
Формат: Artigo
Язык:Inglês
Опубликовано: 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4573582/
https://ncbi.nlm.nih.gov/pubmed/26228140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaa0079
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