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S-Nitrosylation links obesity-associated inflammation to endoplasmic reticulum dysfunction

The association between inflammation and endoplasmic reticulum (ER) stress has been observed in many diseases. However, if and how chronic inflammation regulates the unfolded protein response (UPR) and alters ER homeostasis in general, or in the context of chronic disease, remains unknown. Here, we...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Science
Prif Awduron: Yang, Ling, Calay, Ediz S., Fan, Jason, Arduini, Alessandro, Kunz, Ryan C., Gygi, Steven P., Yalcin, Abdullah, Fu, Suneng, Hotamisligil, Gökhan S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4573582/
https://ncbi.nlm.nih.gov/pubmed/26228140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaa0079
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