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S-Nitrosylation links obesity-associated inflammation to endoplasmic reticulum dysfunction

The association between inflammation and endoplasmic reticulum (ER) stress has been observed in many diseases. However, if and how chronic inflammation regulates the unfolded protein response (UPR) and alters ER homeostasis in general, or in the context of chronic disease, remains unknown. Here, we...

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Vydáno v:Science
Hlavní autoři: Yang, Ling, Calay, Ediz S., Fan, Jason, Arduini, Alessandro, Kunz, Ryan C., Gygi, Steven P., Yalcin, Abdullah, Fu, Suneng, Hotamisligil, Gökhan S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4573582/
https://ncbi.nlm.nih.gov/pubmed/26228140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaa0079
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