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Polysome Profiling in Liver Identifies Dynamic Regulation of Endoplasmic Reticulum Translatome by Obesity and Fasting

Obesity-associated metabolic complications are generally considered to emerge from abnormalities in carbohydrate and lipid metabolism, whereas the status of protein metabolism is not well studied. Here, we performed comparative polysome and associated transcriptional profiling analyses to study the...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Fu, Suneng, Fan, Jason, Blanco, Joshua, Gimenez-Cassina, Alfredo, Danial, Nika N., Watkins, Steve M., Hotamisligil, Gökhan S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3426552/
https://ncbi.nlm.nih.gov/pubmed/22927828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002902
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