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How to Inactivate Human Ubiquitin E3 Ligases by Mutation
E3 ubiquitin ligases are the ultimate enzymes involved in the transfer of ubiquitin to substrate proteins, a process that determines the fate of the modified protein. Numerous diseases are caused by defects in the ubiquitin-proteasome machinery, including when the activity of a given E3 ligase is ha...
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| Pubblicato in: | Front Cell Dev Biol |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Frontiers Media S.A.
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7010608/ https://ncbi.nlm.nih.gov/pubmed/32117970 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.00039 |
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