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How to Inactivate Human Ubiquitin E3 Ligases by Mutation

E3 ubiquitin ligases are the ultimate enzymes involved in the transfer of ubiquitin to substrate proteins, a process that determines the fate of the modified protein. Numerous diseases are caused by defects in the ubiquitin-proteasome machinery, including when the activity of a given E3 ligase is ha...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Front Cell Dev Biol
Main Authors: Garcia-Barcena, Cristina, Osinalde, Nerea, Ramirez, Juanma, Mayor, Ugo
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7010608/
https://ncbi.nlm.nih.gov/pubmed/32117970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.00039
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