The ubiquitin ligase Ariadne-1 regulates neurotransmitter release via ubiquitination of NSF

Ariadne-1 (Ari-1) is an E3 ubiquitin-ligase essential for neuronal development, but whose neuronal substrates are yet to be identified. To search for putative Ari-1 substrates, we used an in vivo ubiquitin biotinylation strategy coupled to quantitative proteomics of Drosophila heads. We identified 1...

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Publicat a:J Biol Chem
Autors principals: Ramírez, Juanma, Morales, Miguel, Osinalde, Nerea, Martínez-Padrón, Imanol, Mayor, Ugo, Ferrús, Alberto
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2021
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7960542/
https://ncbi.nlm.nih.gov/pubmed/33581113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100408
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