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Following Ariadne's thread: a new perspective on RBR ubiquitin ligases
Ubiquitin signaling pathways rely on E3 ligases for effecting the final transfer of ubiquitin from E2 ubiquitin conjugating enzymes to a protein target. Here we re-evaluate the hybrid RING/HECT mechanism used by the E3 family RING-between-RINGs (RBRs) to transfer ubiquitin to substrates. We place RB...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3305615/ https://ncbi.nlm.nih.gov/pubmed/22420831 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1741-7007-10-24 |
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