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Conformational flexibility within the small domain of human serine racemase

Serine racemase (SR) is a pyridoxal 5′-phosphate (PLP)-containing enzyme that converts l-serine to d-serine, an endogenous co-agonist for the N-methyl-d-aspartate receptor (NMDAR) subtype of glutamate ion channels. SR regulates d-serine levels by the reversible racemization of l-serine to d-serine,...

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Bibliografiske detaljer
Udgivet i:Acta Crystallogr F Struct Biol Commun
Main Authors: Koulouris, Chloe R., Bax, Benjamin D., Atack, John R., Roe, S. Mark
Format: Artigo
Sprog:Inglês
Udgivet: International Union of Crystallography 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7010357/
https://ncbi.nlm.nih.gov/pubmed/32039887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X20001193
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