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The Energy Landscape of Human Serine Racemase
Human serine racemase is a pyridoxal 5′-phosphate (PLP)-dependent dimeric enzyme that catalyzes the reversible racemization of L-serine and D-serine and their dehydration to pyruvate and ammonia. As D-serine is the co-agonist of the N-methyl-D-aspartate receptors for glutamate, the most abundant exc...
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| Publicado no: | Front Mol Biosci |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6333871/ https://ncbi.nlm.nih.gov/pubmed/30687716 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2018.00112 |
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