The Energy Landscape of Human Serine Racemase

Human serine racemase is a pyridoxal 5′-phosphate (PLP)-dependent dimeric enzyme that catalyzes the reversible racemization of L-serine and D-serine and their dehydration to pyruvate and ammonia. As D-serine is the co-agonist of the N-methyl-D-aspartate receptors for glutamate, the most abundant exc...

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Détails bibliographiques
Publié dans:Front Mol Biosci
Auteurs principaux: Raboni, Samanta, Marchetti, Marialaura, Faggiano, Serena, Campanini, Barbara, Bruno, Stefano, Marchesani, Francesco, Margiotta, Marilena, Mozzarelli, Andrea
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2019
Sujets:
Molecular Biosciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6333871/
https://ncbi.nlm.nih.gov/pubmed/30687716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2018.00112
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