Cerebrospinal fluid tau fragment correlates with tau PET: a candidate biomarker for tangle pathology

To date, there is no validated fluid biomarker for tau pathology in Alzheimer’s disease, with contradictory results from studies evaluating the correlation between phosphorylated tau in CSF with tau PET imaging. Tau protein is subjected to proteolytic processing into fragments before being secreted...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Brain
Päätekijät: Blennow, Kaj, Chen, Chun, Cicognola, Claudia, Wildsmith, Kristin R, Manser, Paul T, Bohorquez, Sandra M Sanabria, Zhang, Zhentao, Xie, Boer, Peng, Junmin, Hansson, Oskar, Kvartsberg, Hlin, Portelius, Erik, Zetterberg, Henrik, Lashley, Tammaryn, Brinkmalm, Gunnar, Kerchner, Geoffrey A, Weimer, Robby M, Ye, Keqiang, Höglund, Kina
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2020
Aiheet:
Original Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7009597/
https://ncbi.nlm.nih.gov/pubmed/31834365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awz346
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