Cerebrospinal fluid tau fragment correlates with tau PET: a candidate biomarker for tangle pathology

To date, there is no validated fluid biomarker for tau pathology in Alzheimer’s disease, with contradictory results from studies evaluating the correlation between phosphorylated tau in CSF with tau PET imaging. Tau protein is subjected to proteolytic processing into fragments before being secreted...

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Detalhes bibliográficos
Publicado no:Brain
Main Authors: Blennow, Kaj, Chen, Chun, Cicognola, Claudia, Wildsmith, Kristin R, Manser, Paul T, Bohorquez, Sandra M Sanabria, Zhang, Zhentao, Xie, Boer, Peng, Junmin, Hansson, Oskar, Kvartsberg, Hlin, Portelius, Erik, Zetterberg, Henrik, Lashley, Tammaryn, Brinkmalm, Gunnar, Kerchner, Geoffrey A, Weimer, Robby M, Ye, Keqiang, Höglund, Kina
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7009597/
https://ncbi.nlm.nih.gov/pubmed/31834365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awz346
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