Meta-Analysis of Genome-Wide Association and Gene Expression Studies Implicates Donor T Cell Function and Cytokine Pathways in Acute GvHD

Graft-vs.-host disease (GvHD) is a major complication after allogeneic hematopoietic stem cell transplantation that causes mortality and severe morbidity. Genetic disparities in human leukocyte antigens between the recipient and donor are known contributors to the risk of the disease. However, the o...

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Vydáno v:Front Immunol
Hlavní autoři: Hyvärinen, Kati, Koskela, Satu, Niittyvuopio, Riitta, Nihtinen, Anne, Volin, Liisa, Salmenniemi, Urpu, Putkonen, Mervi, Buño, Ismael, Gallardo, David, Itälä-Remes, Maija, Partanen, Jukka, Ritari, Jarmo
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7008714/
https://ncbi.nlm.nih.gov/pubmed/32117222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00019
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