Immunomonitoring of MSC-Treated GvHD Patients Reveals Only Moderate Potential for Response Prediction but Indicates Treatment Safety

Mesenchymal stromal cells (MSCs) are used as salvage therapy to treat steroid-refractory acute graft-versus-host disease (aGvHD). We studied the immunological response to MSC treatment in 16 aGvHD patients by assessing lymphocyte profiles and three proposed aGvHD serum markers during the MSC treatme...

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Detalhes bibliográficos
Publicado no:Mol Ther Methods Clin Dev
Main Authors: Keto, Joni, Kaartinen, Tanja, Salmenniemi, Urpu, Castrén, Johanna, Partanen, Jukka, Hänninen, Arno, Korhonen, Matti, Lähteenmäki, Kaarina, Itälä-Remes, Maija, Nystedt, Johanna
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5834657/
https://ncbi.nlm.nih.gov/pubmed/29516024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2018.02.001
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