Computational Analysis of HLA-presentation of Non-synonymous Recipient Mismatches Indicates Effect on the Risk of Chronic Graft-vs.-Host Disease After Allogeneic HSCT

Genetic mismatches in protein coding genes between allogeneic hematopoietic stem cell transplantation (allo-HSCT) recipient and donor can elicit an alloimmunity response via peptides presented by the recipient HLA receptors as minor histocompatibility antigens (mHAs). While the impact of individual...

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Foilsithe in:Front Immunol
Main Authors: Ritari, Jarmo, Hyvärinen, Kati, Koskela, Satu, Niittyvuopio, Riitta, Nihtinen, Anne, Salmenniemi, Urpu, Putkonen, Mervi, Volin, Liisa, Kwan, Tony, Pastinen, Tomi, Itälä-Remes, Maija, Partanen, Jukka
Formáid: Artigo
Teanga:Inglês
Foilsithe: Frontiers Media S.A. 2019
Ábhair:
Immunology
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6646417/
https://ncbi.nlm.nih.gov/pubmed/31379830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01625
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