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ApoE in brain pericytes regulates endothelial function in an isoform-dependent manner by modulating basement membrane components
OBJECTIVE: The ε4 allele of the APOE gene (APOE4) is the strongest genetic risk factor for Alzheimer’s disease when compared to the common ε3 allele. Although there has been significant progress in understanding how apolipoprotein E4 (apoE4) drives amyloid pathology, its effects on amyloid-independe...
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| Publicado no: | Arterioscler Thromb Vasc Biol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7007705/ https://ncbi.nlm.nih.gov/pubmed/31665905 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.119.313169 |
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