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ApoE in brain pericytes regulates endothelial function in an isoform-dependent manner by modulating basement membrane components
OBJECTIVE: The ε4 allele of the APOE gene (APOE4) is the strongest genetic risk factor for Alzheimer’s disease when compared to the common ε3 allele. Although there has been significant progress in understanding how apolipoprotein E4 (apoE4) drives amyloid pathology, its effects on amyloid-independe...
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| 出版年: | Arterioscler Thromb Vasc Biol |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7007705/ https://ncbi.nlm.nih.gov/pubmed/31665905 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.119.313169 |
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