Chronic Dicer1 deficiency promotes atrophic and neovascular outer retinal pathologies in mice

Degeneration of the retinal pigmented epithelium (RPE) and aberrant blood vessel growth in the eye are advanced-stage processes in blinding diseases such as age-related macular degeneration (AMD), which affect hundreds of millions of people worldwide. Loss of the RNase DICER1, an essential factor in...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Wright, Charles B., Uehara, Hironori, Kim, Younghee, Yasuma, Tetsuhiro, Yasuma, Reo, Hirahara, Shuichiro, Makin, Ryan D., Apicella, Ivana, Pereira, Felipe, Nagasaka, Yosuke, Narendran, Siddharth, Fukuda, Shinichi, Albuquerque, Romulo, Fowler, Benjamin J., Bastos-Carvalho, Ana, Georgel, Philippe, Hatada, Izuho, Chang, Bo, Kerur, Nagaraj, Ambati, Balamurali K., Ambati, Jayakrishna, Gelfand, Bradley D.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7007521/
https://ncbi.nlm.nih.gov/pubmed/31964819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1909761117
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados