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Nucleosomal proofreading of activator–promoter interactions

Specificity in transcriptional regulation is imparted by transcriptional activators that bind to specific DNA sequences from which they stimulate transcription. Specificity may be increased by slowing down the kinetics of regulation: by increasing the energy for dissociation of the activator–DNA com...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Shelansky, Robert, Boeger, Hinrich
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7007518/
https://ncbi.nlm.nih.gov/pubmed/31964832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1911188117
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