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Nucleosomal proofreading of activator–promoter interactions

Specificity in transcriptional regulation is imparted by transcriptional activators that bind to specific DNA sequences from which they stimulate transcription. Specificity may be increased by slowing down the kinetics of regulation: by increasing the energy for dissociation of the activator–DNA com...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Shelansky, Robert, Boeger, Hinrich
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7007518/
https://ncbi.nlm.nih.gov/pubmed/31964832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1911188117
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