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Nucleosomal proofreading of activator–promoter interactions

Specificity in transcriptional regulation is imparted by transcriptional activators that bind to specific DNA sequences from which they stimulate transcription. Specificity may be increased by slowing down the kinetics of regulation: by increasing the energy for dissociation of the activator–DNA com...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Shelansky, Robert, Boeger, Hinrich
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7007518/
https://ncbi.nlm.nih.gov/pubmed/31964832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1911188117
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