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Nucleosome Retention and The Stochastic Nature of Promoter Chromatin Remodeling for Transcription

The rate-limiting step of transcriptional activation in eukaryotes, and thus the critical point for gene regulation, is unknown. Using the inducible PHO5 gene of yeast as a model, we show that essential features of the transcriptional activation process can be described by a small number of simple a...

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Autors principals: Boeger, Hinrich, Griesenbeck, Joachim, Kornberg, Roger D.
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2409070/
https://ncbi.nlm.nih.gov/pubmed/18485878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2008.02.051
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