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Targeting of temperate phages drives loss of type I CRISPR-Cas systems

Upon infection of their host, temperate phages (viruses that infect bacteria) enter either a lytic or a lysogenic cycle. The former results in bacterial cell lysis and phage release (horizontal transmission), while lysogeny is characterized by integration of the phage in the host genome and dormancy...

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Bibliographische Detailangaben
Veröffentlicht in:Nature
Hauptverfasser: Rollie, Clare, Chevallereau, Anne, Watson, Bridget N.J., Chyou, Te-yuan, Fradet, Olivier, McLeod, Isobel, Fineran, Peter C., Brown, Chris M., Gandon, Sylvain, Westra, Edze R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7007301/
https://ncbi.nlm.nih.gov/pubmed/31969710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-020-1936-2
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