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Bacterial biodiversity drives the evolution of CRISPR-based phage resistance

Approximately half of all bacterial species encode CRISPR-Cas adaptive immune systems(1), which provide immunological memory by inserting short DNA sequences from phage and other parasitic DNA elements into CRISPR loci on the host genome(2). Whereas CRISPR loci evolve rapidly in natural environments...

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Bibliografski detalji
Izdano u:Nature
Glavni autori: Alseth, Ellinor O, Pursey, Elizabeth, Luján, Adela M, McLeod, Isobel, Rollie, Clare, Westra, Edze R
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6837874/
https://ncbi.nlm.nih.gov/pubmed/31645729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-019-1662-9
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