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Bacterial biodiversity drives the evolution of CRISPR-based phage resistance
Approximately half of all bacterial species encode CRISPR-Cas adaptive immune systems(1), which provide immunological memory by inserting short DNA sequences from phage and other parasitic DNA elements into CRISPR loci on the host genome(2). Whereas CRISPR loci evolve rapidly in natural environments...
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| Gepubliceerd in: | Nature |
|---|---|
| Hoofdauteurs: | , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2019
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6837874/ https://ncbi.nlm.nih.gov/pubmed/31645729 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-019-1662-9 |
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