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GeneORator: An Effective Strategy for Navigating Protein Sequence Space More Efficiently through Boolean OR-Type DNA Libraries
[Image: see text] Directed evolution requires the creation of genetic diversity and subsequent screening or selection for improved variants. For DNA mutagenesis, conventional site-directed methods implicitly utilize the Boolean AND operator (creating all mutations simultaneously), producing a combin...
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| Publicado no: | ACS Synth Biol |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical
Society
2019
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7007284/ https://ncbi.nlm.nih.gov/pubmed/31132850 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acssynbio.9b00063 |
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