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Ultra-high throughput functional enrichment of large monoamine oxidase (MAO-N) libraries by fluorescence activated cell sorting

Directed evolution enables the improvement and optimisation of enzymes for particular applications and is a valuable tool for biotechnology and synthetic biology. However, studies are often limited in their scope by the inability to screen very large numbers of variants to identify improved enzymes....

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Pubblicato in:Analyst
Autori principali: Sadler, Joanna C., Currin, Andrew, Kell, Douglas B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Royal Society of Chemistry 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6156879/
https://ncbi.nlm.nih.gov/pubmed/30199078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8an00851e
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