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Deep learning models predict regulatory variants in pancreatic islets and refine type 2 diabetes association signals
Genome-wide association analyses have uncovered multiple genomic regions associated with T2D, but identification of the causal variants at these remains a challenge. There is growing interest in the potential of deep learning models - which predict epigenome features from DNA sequence - to support i...
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| Publicat a: | eLife |
|---|---|
| Autors principals: | , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
eLife Sciences Publications, Ltd
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7007221/ https://ncbi.nlm.nih.gov/pubmed/31985400 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.51503 |
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