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Amino acid residues involved in the heparin-binding activity of murine IL-12 in the context of an antibody-cytokine fusion protein
An antibody-cytokine fusion protein, composed of the murine single-chain cytokine interleukin-12 (IL-12) genetically fused to a human IgG3 specific for the human tumor-associated antigen HER2/neu maintains antigen binding, cytokine, bioactivity, and IL-12 heparin-binding activity. This latter proper...
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| 發表在: | Cytokine |
|---|---|
| Main Authors: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2019
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7007190/ https://ncbi.nlm.nih.gov/pubmed/31121497 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cyto.2019.04.004 |
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