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Determining sequencing depth in a single-cell RNA-seq experiment
An underlying question for virtually all single-cell RNA sequencing experiments is how to allocate the limited sequencing budget: deep sequencing of a few cells or shallow sequencing of many cells? Here we present a mathematical framework which reveals that, for estimating many important gene proper...
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| Publicado en: | Nat Commun |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7005864/ https://ncbi.nlm.nih.gov/pubmed/32034137 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-14482-y |
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