Deterministic column subset selection for single-cell RNA-Seq

Analysis of single-cell RNA sequencing (scRNA-Seq) data often involves filtering out uninteresting or poorly measured genes and dimensionality reduction to reduce noise and simplify data visualization. However, techniques such as principal components analysis (PCA) fail to preserve non-negativity an...

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Enregistré dans:
Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: McCurdy, Shannon R., Ntranos, Vasilis, Pachter, Lior
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2019
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6347249/
https://ncbi.nlm.nih.gov/pubmed/30682053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0210571
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