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Deterministic column subset selection for single-cell RNA-Seq

Analysis of single-cell RNA sequencing (scRNA-Seq) data often involves filtering out uninteresting or poorly measured genes and dimensionality reduction to reduce noise and simplify data visualization. However, techniques such as principal components analysis (PCA) fail to preserve non-negativity an...

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Veröffentlicht in:PLoS One
Hauptverfasser: McCurdy, Shannon R., Ntranos, Vasilis, Pachter, Lior
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6347249/
https://ncbi.nlm.nih.gov/pubmed/30682053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0210571
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