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High-throughput identification of post-transcriptional utrophin up-regulators for Duchenne muscle dystrophy (DMD) therapy

Upregulation of endogenous utrophin offers great promise for treating DMD, as it can functionally compensate for the lack of dystrophin caused by DMD gene mutations, without the immunogenic concerns associated with delivering dystrophin. However, post-transcriptional repression mechanisms targeting...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Loro, Emanuele, Sengupta, Kasturi, Bogdanovich, Sasha, Whig, Kanupriya, Schultz, David C., Huryn, Donna M., Khurana, Tejvir S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2020
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7005813/
https://ncbi.nlm.nih.gov/pubmed/32034254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-58737-6
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