Cis- and trans-regulations of pre-mRNA splicing by RNA editing enzymes influence cancer development

RNA editing and splicing are the two major processes that dynamically regulate human transcriptome diversity. Despite growing evidence of crosstalk between RNA editing enzymes (mainly ADAR1) and splicing machineries, detailed mechanistic explanations and their biological importance in diseases, such...

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Veröffentlicht in:Nat Commun
Hauptverfasser: Tang, Sze Jing, Shen, Haoqing, An, Omer, Hong, HuiQi, Li, Jia, Song, Yangyang, Han, Jian, Tay, Daryl Jin Tai, Ng, Vanessa Hui En, Bellido Molias, Fernando, Leong, Ka Wai, Pitcheshwar, Priyankaa, Yang, Henry, Chen, Leilei
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7005744/
https://ncbi.nlm.nih.gov/pubmed/32034135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-14621-5
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