Cis-splicing and Translation of the Pre-Trans-splicing Molecule Combine With Efficiency in Spliceosome-mediated RNA Trans-splicing

Muscular dystrophies are a group of genetically distinct diseases for which no treatment exists. While gene transfer approach is being tested for several of these diseases, such strategies can be hampered when the size of the corresponding complementary DNA (cDNA) exceeds the packaging capacity of a...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Monjaret, François, Bourg, Nathalie, Suel, Laurence, Roudaut, Carinne, Le Roy, Florence, Richard, Isabelle, Charton, Karine
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2014
Sujets:
Original Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4048894/
https://ncbi.nlm.nih.gov/pubmed/24618805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2014.35
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