Cis-splicing and Translation of the Pre-Trans-splicing Molecule Combine With Efficiency in Spliceosome-mediated RNA Trans-splicing

Muscular dystrophies are a group of genetically distinct diseases for which no treatment exists. While gene transfer approach is being tested for several of these diseases, such strategies can be hampered when the size of the corresponding complementary DNA (cDNA) exceeds the packaging capacity of a...

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Detalhes bibliográficos
Main Authors: Monjaret, François, Bourg, Nathalie, Suel, Laurence, Roudaut, Carinne, Le Roy, Florence, Richard, Isabelle, Charton, Karine
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4048894/
https://ncbi.nlm.nih.gov/pubmed/24618805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2014.35
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